Alzheimer's Disease Cortical Membrane and Cholesterol

Small angle X-ray analysis of Alzheimer's Disease lipid membranes showed significant structure changes. Role of cholesterol in these changes. Alterations in the composition and structure of the membrane bilayer may play role in pathophysiology of AD by altering activity and catabolism of membrane-bound proteins--most notably the beta-amyloid precursor protein.

In: Neurobiology of Aging (1992): 413-419

https://www.scribd.com/document/17755698/Changes-in-the-Alzheimer-s-Disease-Cortical-Membrane-and-Choleterol

Biochemical and structural analysis of lipid membranes from temporal gyrus and cerebellum of Alzheimer's diseased brains

Mason, R.P., Shajenko, L., Chambers, T.E., Grazioso, H.J., Shoemaker, W.J.,
and Herbette, L.G., Biochemical and structural analysis of lipid membranes
from temporal gyrus and cerebellum of Alzheimer's diseased brains, Biophysical
Journal, vol 59 (1991), 592a

https://www.cell.com/biophysj/pdf/S0006-3495%2891%2982265-2.pdf